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Discover why industry-leading companies across the globe love our knowledge. IPinfo’s accurate insights fuel use cases from cybersecurity, information enrichment, web personalization, and far more. Effects of testosterone on coronary vasomotor regulation in men with coronary heart disease. Manifestation of severe coronary coronary heart illness after anabolic drug abuse. Relationship between endogenous sex hormone levels, lipoproteins and coronary atherosclerosis in males undergoing coronary angiography. Basaria S, Dobs AS. Risks versus benefits of testosterone therapy in elderly men.
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However, testosterone in physiologic doses could even be helpful in patients with angina , have larger ischemic thresholds and improved high quality of life . Short-term intracoronary administration of testosterone induces coronary artery dilation and will increase coronary blood flow in men with established coronary artery illness . Therefore, an interaction of endogenous components of the patient’s danger profile in addition to the testosterone dosing could additionally be issues of whether antagonistic events occur. Erythrocytosis has been reported as a potential effect of testosterone, which could be helpful in patients with anemia. The best threat of erythrocytosis happens with injectable forms of testosterone in contrast with transdermal preparations, particularly in supraphysiologic doses. An increase of up to 44% of the baseline hematocrit has been reported . Moreover, testosterone has been used within the treatment of decreased muscle mass and bone density in addition to anemia.
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In addition, the info out there within the literature doesn’t account for the steroid sort or dose, as neither may be recognized. Patients also could additionally be taking concomitant stimulants, similar to ephedra, which might confound information and the potential for opposed events. It is most likely going that the frequency of cardiac occasions is underreported in the medical literature. Supraphysiologic doses of anabolic-androgenic steroids , which embody more than 30 natural and synthetic derivatives of testosterone, might cause a large spectrum of clinical sequalae.